Elephantiasis neuromatosa

Giant elephantiasis neuromatosa in the setting of neurofibromatosis type 1: A case report.

Elephantiasis neuromatosa (EN) can arise from a plexiform neurofibroma of the superficial and deep nerves developing from a hyperproliferation of the perineural connective tissue infiltrating adjacent fat and muscles. To date, the clinical association between EN and neurofibromatosis type 1 (NF1) has been poorly defined, particularly with regard to the role of lymphatic alterations and the cons...

A case report of surgical debulking for a huge mass of elephantiasis neuromatosa

Achievement of a safe outcome for an extensive mass with hypervascularity in the extremities requires a surgical team skilled in musculoskeletal oncology. We report debulking surgery for a huge mass of elephantiasis neuromatosa in the right leg of a 56-year old man using the novel Ligasure® vessel sealing system.

NF1 truncating mutations associated to aggressive clinical phenotype with elephantiasis neuromatosa and solid malignancies.

BACKGROUND/AIM Von Recklinghausen disease is a syndrome characterized by a wide phenotypic variability giving rise to both, cutaneous and visceral benign and malignant neoplasms. The first include cutaneous neurofibromas, subcutaneous and plexiform neurofibromas. The latter can undergo malignant transformation and/or determine elephantiasis neuromatosa. Visceral tumors may include malignant per...

Elephantiasis

Scrotal Elephantiasis

an early mpjfcality of twenty-seven per cent, in sixty-one cases of operation for Scrotal Elephantiasis reported by Fayrer Oh" referring to my published record of these cases, I obsor-ve that the total number of cases operated upon during, .the yea-s, 1859 to 1871 amounted to 193, of which 35, or a fraction over 18 per cent., proved fatal. This is befit'dr than represented by Koch's, as above q...